The signifigance of \(A_D\) the Durian constant,
\(A_D=\cfrac{4}{3}\pi (2c)^3=9.029022e26\)
is, a contained system, where the system has integer multiples of \(A_D\) number of particles in it,
\(N=nA_D\)
\(n=1,2,3...\)
where \(N\) is the total number of particles in the system.
Entanglement results in energy loss from the system. In a contained system, it can be assumed that entanglement is within the system that no energy is loss to outside the system.
A non-contained system is when the number of particles in the system, \(N\) is not an integer multiples of the Durian constant, where part of the entanglement is outside of the system.
There is no certainty that all entanglement is within a contained system, only greater assurance that the particles inside, subjected to the same physical conditions, are entangled within the system.
Since, entanglement loss is not a defined problem, this is the undefined solution to a unappreciated problem.