The Botulinum toxins are large neurotoxic proteins made up of a light chain and a heavy chain linked by a disulfide bond of length 2.055A. This allosteric disulfide bond was termed labile, a property used to identify functional disulfides. (Identification of allosteric disulfides from labile bonds in X-ray structures by Aster E. Pijning, Joyce Chiu, Reichelle X. Yeo, Jason W. H. Wong and Philip J. Hogg, Published:07 February 2018 https://doi.org/10.1098/rsos.171058)
fres=0.122cBL
fres=0.122∗2997924582.055∗1010
fres1015=177.979Hz
Breaking S-S disulfide in Botulinum Toxins 177-979 Hz
Unfortunately, disulfide bonds are everywhere,
"Five known allosteric disulfides were among the 511 labile bonds, which is a validation of this approach for identifying functional disulfides. These are the –RHstaple bonds in methionine aminopeptidase 2 [23], botulinum neurotoxins [24] and transglutaminase 2 [25], the –/+RHhook disulfides in plasminogen [26] and Lon protease [27] and the –LHhook bonds in DNA repair protein XRCC1 [28] and plasminogen [26] (electronic supplementary material, table S3)."
from the publication cited above. Use this frequency with due caution!
For more conventional frequencies against Botulinum,
Goodnight...
